Table 2. Clinico-pathological features in relation to pSrc-Y416.
| Variables | All cases, n (%) | pSrcY416 (+), n (%) | pSrcY416 (−), n (%) | *P-value |
|---|---|---|---|---|
| Number |
278 (100) |
105 (37.8) |
173 (62.2) |
|
|
Age (years) | ||||
| <50 | 88 (31.7) | 34 (36.2) | 54 (32) | |
| ⩾50 | 175 (62.9) | 60 (63.8) | 115 (68) | 0.487 |
| Unknown |
15 (5.4) |
|
|
|
|
Size | ||||
| 5–20 mm | 103 (37.1) | 45 (48.9) | 58 (36.3) | |
| >20 mm | 149 (53.6) | 47 (51.1) | 102 (63.8) | 0.049 |
| Unknown |
26 (9.4) |
|
|
|
|
Grade | ||||
| 1 | 12 (4.3) | 2 (1.9) | 10 (5.8) | |
| 2 | 93 (33.5) | 33 (31.4) | 61 (35.3) | |
| 3 |
171 (61.5) |
70 (66.7) |
102 (59) |
0.203 |
|
Necrosis | ||||
| Absent | 81 (29.1) | 19 (35.8) | 62 (52.5) | |
| Present | 90 (32.4) | 34 (64.2) | 56 (47.5) | 0.043 |
| Unknown |
107 (38.5) |
|
|
|
|
LVI | ||||
| Absent | 203 (73) | 70 (71.4) | 133 (79.6) | |
| Present | 62 (22.3) | 28 (28.6) | 34 (20.4) | 0.127 |
| Unknown |
13 (4.7) |
|
|
|
|
LN status | ||||
| Negative | 118 (42.4) | 46 (46.9) | 72 (43.4) | |
| Positive | 146 (52.5) | 52 (53.1) | 94 (56.6) | 0.573 |
| Unknown |
14 (5) |
|
|
|
|
Stage | ||||
| I | 61 (21.9) | 23 (22.8) | 38 (22.6) | |
| II | 109 (39.2) | 39 (38.6) | 70 (41.7) | |
| III | 89 (32) | 33 (32.7) | 56 (33.3) | |
| IV | 10 (3.6) | 6 (5.9) | 4 (2.4) | 0.512 |
| Unknown | 9 (3.2) | |||
Abbreviations: LN=lymph nodes; LVI=lymph vascular invasion.
*All comparisons by Chi2 or Fisher tests.