Table 2. Gene promoters selected for the validation phase.

Symbol	Gene ID	Gene name	Bmin TSS200	Bmax TSS200	pmin	TSS200 probes	TSS200 significant probes
APC	NM_000038	Adenomatous polyposis coli	0.144	0.24	0.00017	9	9
mir10B	NR_029609	MicroRNA 10b (MIR10B)	0.190	0.26	6.06E−05	6	6
TACC2	NM_006997	Transforming, acidic coiled-coil containing protein 2	0.139	0.30	0.00014	5	5
HES5	NM_001010926	Hairy and enhancer of split 5 (Drosophila)	0.21	0.28	7.69E−05	4	4
DGKZ	NM_001105540	Diacylglycerol kinase, zeta	0.164	0.191	0.00010	3	3
RARB	NM_000965	Retinoic acid receptor, beta	0.128	0.198	0.00012	3	3
ITGB2	NM_000211	Integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	0.148	0.22	0.0040	3	3
FAXDC2	NM_032385	Fatty acid hydroxylase domain containing 2	0.125	0.139	0.0069	2	2

Bmin and Bmax denote the lowest and the highest difference, respectively, between observed methylation rates in prostates resected from PCa patients and BPH patients for all probes mapping to the TSS200 region of a given gene. pmin denotes the lowest P-value (corrected) among all probes mapping for the given TSS200 region.