Table 5. Ovarian cancer patients with a complete or partial objective response by germline BRCA (gBRCA) status and platinum sensitivity.
| |
gBRCA mutation status |
|
||
|---|---|---|---|---|
| Platinum sensitivity | gBRCAm (n=18) | gBRCAwt (n=1) | Unknown (n=7) | Total (n=26) |
| Platinum sensitive (n=14) |
8/12 |
1/1 |
1/1 |
10/14 (71%) |
| Platinum resistant (n=12) |
3/6 |
0/0 |
0/6 |
3/12 (25%) |
| Total (n=26) | 11/18 (61%) | 1/1 (100%) | 1/7 (14%) | 13/26 (50%) |
Abbreviations: gBRCA=germline BRCA; gBRCAm=gBRCA mutated; gBRCAwt=gBRCA wild type (no mutation).