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LP-FTY720 down-regulates Mcl-1 in CLL patient cells. (A) Representative western blot of Mcl-1 protein level after treating CLL cells at 106 cell/mL with 5 μM FTY720 for 20 h. (B) Relative percentage of Mcl-1 down-regulation levels of CLL patient cells (n = 4).
