. Author manuscript; available in PMC: 2014 Sep 1.

Published in final edited form as: Cancer Discov. 2013 Dec 19;4(3):348–361. doi: 10.1158/2159-8290.CD-13-0349

Table 1.

Comparison of methylation heterogeneity with patient characteristics and prognostic indicators

	Low DNA methylation heterogeneity no. (%)	High DNA methylation heterogeneity no. (%)	P
Patient characteristics
Age at diagnosis (y ± SD)	55.8 ± 11.8	59.9 ± 10.6	n.s.
Sex (female)	10 (33)	15 (48)	n.s.
Pretreatment (yes)	6 (19)	13 (42)	0.014

Prognostic indicators
IGHV unmutated	8 (35)	11 (79)	<0.01
ZAP70 low methylation	7 (30)	9 (69)	0.024
Cytogenetics (NK, sole −13q)	14 (61)	9 (69)	n.s.

Abbreviation: n.s., not significant.