Patient features may have been present in the past or at present.
Clinical case presentation and progress (include disease duration): 60 year old Caucasian female referred with anti-centromere antibody
Clinical features
□ Yes	⊠ No	Skin thickening
Describe location, extent, progression:
□ Yes	⊠ No	Abnormal nailfold capillaries consistent with scleroderma
⊠ Yes	□ No	Calcinosis
□ Yes	⊠ No	Digital pulp loss or acro-osteolysis
□ Yes	⊠ No	Dysphagia for solids
□ Yes	⊠ No	Esophageal dilation
□ Yes	⊠ No	Finger flexion contracture
□ Yes	⊠ No	Finger tip ulcers or pitting scars
⊠ Yes	□ No	Puffy fingers
□ Yes	⊠ No	Interstitial lung disease or pulmonary fibrosis
□ Yes	⊠ No	Pulmonary arterial hypertension
⊠ Yes	□ No	Gastro-esophageal reflux disease
□ Yes	⊠ No	Raynaud’s phenomenon
□ Yes	⊠ No	Renal crisis
□ Yes	⊠ No	Telangiectasias
□ Yes	⊠ No	Tendon or bursal friction rubs
Laboratory features
⊠ Positive	□ Negative	Antinuclear antibody
⊠ Positive	□ Negative	Anti-centromere antibody
□ Positive	⊠ Negative	Anti-topoisomerase-I antibody
□ Positive	⊠ Negative	Anti-PM-Scl antibody
□ Positive	⊠ Negative	Anti-RNA polymerase III antibody
Investigations
□ Yes	⊠ No	DLCO < 80% predicted
□ Yes	⊠ No	FVC < 80% predicted
Any other information which may be relevant to the probability this patient has Systemic Sclerosis: