Patient features may have been present in the past or at present. | ||
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Clinical case presentation and progress (include disease duration): 56 year old Caucasian male with rapidly progressive skin thickening and induration over 12 weeks | ||
Clinical features | ||
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⊠ Yes | □ No | Skin thickening |
Describe location, extent, progression: Skin involvement of wrists, forearms, upper chest, proximal legs, distal legs and ankles. No skin involvement of hands, feet nor face. | ||
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□ Yes | ⊠ No | Abnormal nailfold capillaries consistent with scleroderma |
□ Yes | ⊠ No | Calcinosis |
□ Yes | ⊠ No | Digital pulp loss or acro-osteolysis |
□ Yes | ⊠ No | Dysphagia for solids |
□ Yes | ⊠ No | Esophageal dilation |
□ Yes | ⊠ No | Finger flexion contracture |
□ Yes | ⊠ No | Finger tip ulcers or pitting scars |
□ Yes | ⊠ No | Puffy fingers |
□ Yes | ⊠ No | Interstitial lung disease or pulmonary fibrosis |
⊠ Yes | □ No | Pulmonary arterial hypertension |
⊠ Yes | □ No | Gastro-esophageal reflux disease |
□ Yes | ⊠ No | Raynaud’s phenomenon |
□ Yes | ⊠ No | Renal crisis |
□ Yes | ⊠ No | Telangiectasias |
□ Yes | ⊠ No | Tendon or bursal friction rubs |
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Laboratory features | ||
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⊠ Positive | □ Negative | Antinuclear antibody |
□ Positive | ⊠ Negative | Anti-centromere antibody |
□ Positive | ⊠ Negative | Anti-topoisomerase-I antibody |
□ Positive | ⊠ Negative | Anti-PM-Scl antibody |
□ Positive | ⊠ Negative | Anti-RNA polymerase III antibody |
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Investigations | ||
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□ Yes | ⊠ No | DLCO < 80% predicted |
□ Yes | ⊠ No | FVC < 80% predicted |
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Any other information which may be relevant to the probability this patient has Systemic Sclerosis: |