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. Author manuscript; available in PMC: 2014 Aug 16.
Published in final edited form as: Lancet Oncol. 2013 Dec 10;15(1):48–58. doi: 10.1016/S1470-2045(13)70513-8

Figure 2. Overall responses by subgroup analyses.

Figure 2

Overall responses defined as complete or partial responses according to International Workshop on Chronic Lymphocytic Leukemia criteria. ECOG=Eastern Cooperative Oncology Group. IgHV=immunoglobulin variable heavy chain. *95% exact binomial CI. †Haemoglobin ≤110 g/L or platelet counts of ≤100 × 109 platelets per L or absolute neutrophil count ≤1·5 × 109 cells per L. ‡ZAP-70 methylated refers to CpG3 ≥15%, non-methylated refers to CpG3 <15%; data were not available for one patient.