Table 2.

Generality of the Catalyzed P-3CCR Using Cu(II) Indan Pybox Catalyst

entrya	R1	R2	R3	product	% yieldb	% eec
1	PhCH2 (9)	2-furyl (10)	PhCH2 (11)	16	83	62 (R)d
2	PhCH2 (9)	BnOCH2 (6)	PhCH2 (11)	17	87	72
3	Ph (5)	2-thiophenecarboxyl (12)	t-butyl (13)	18	95	82 (R)
4	Ph (5)	BnOCH2 (6)	n-butyl (14)	19	87	88
5	Ph (5)	BnOCH2 (6)	n-pentyl (15)	20	83	89
6	Ph (5)	BnOCH2 (6)	PhCH2 (11)	21	89	93
7	Ph (5)	BnOCH2 (6)	t-butyl (13)	22	95	98
8	Ph (5)	2-furyl (10)	p-MeOPh (7)	23	98	91 (R)
9	Ph (5)	2-furyl (10)	PhCH2 (11)	24	90	75 (R)
10	Ph (5)	2-furyl (10)	t-butyl (13)	25	97	89 (R)
11	Ph (5)	2-furyl (10)	n-butyl (14)	26	82	78 (R)
12	Ph (5)	2-furyl (10)	n-pentyl (15)	27	82	78 (R)
13	Ph (5)	2-thiophenecarboxyl (12)	p-MeOPh (7)	28	95	89 (R)
14	Ph (5)	2-thiophenecarboxyl (12)	PhCH2 (11)	29	87	75 (R)
15	Ph (5)	2-thiophenecarboxyl (12)	n-butyl (14)	30	76	64 (R)
16	Ph (5)	2-thiophenecarboxyl (12)	n-pentyl (15)	31	75	60 (R)

^a[0.15 M] final.

^bIsolated yield.

^cSee the Supporting Information for HPLC conditions.

^dInferred absolute stereochemistry based on X-ray crystal analysis with 5-bromo-2-furaldehyde as the substrate.