Table 1. Phenotype Comparison of the Utah and AREDS Cohorts.
Variable | Utah | AREDS | ||
---|---|---|---|---|
|
|
|||
Cases | Controls | Cases | Controls | |
Total, No. | 744 (208 GA and 536 CNV) | 377 | 591 (133 GA and 458 CNV) | 132 |
Sex, % | ||||
Female | 53.6 | 60.7 | 55.5 | 57.6 |
Male | 46.4 | 39.3 | 44.5 | 42.4 |
Age, mean (SD), y | 79.1 (9.4) | 74.4 (7.1) | 70.2 (5.1) | 67.0 (4.3) |
Smoking, % | ||||
Never | 62.6 | 67.0 | 37.6 | 51.5 |
Ever | 31.3 | 31.1 | 49.7 | 38.6 |
Current | 6.1 | 1.9 | 12.7 | 9.8 |
Abbreviations: AREDS, Age-Related Eye Disease Study; CNV, choroidal neovascularization; GA, geographic atrophy.