Table 2. Association of 8 SNPs Between Patients With Advanced Age-Related Macular Degeneration and Control Individuals^a.

Gene	SNP	Allele	Cases (n = 1335)	Controls (n=509)	OR (95% CI)
CFH	rs1061170	C	0.59	0.37	2.45 (2.11-2.84)
CFH	rs2274700	C	0.78	0.56	2.76 (2.36-3.22)
CFH	rs1410996	C	0.78	0.59	2.52 (2.16-2.94)
C2	rs9332739	C	0.03	0.05	0.55 (0.38-0.81)
CFB	rs641153	T	0.05	0.09	0.54 (0.41-0.71)
HTRA1/LOC387715	rs10490924	T	0.41	0.19	2.94 (2.47-3.50)
HTRA1/LOC387715	rs11200638	A	0.42	0.22	2.61 (0.21-3.09)
C3	rs2230199	G	0.28	0.19	1.62 (1.36-1.93)

Abbreviations: CI, confidence interval; OR, odds ratio; SNP, single-nucleotide polymorphism.

^aP< .001 for all.