Figure 5. Temperature dependence of Kd in WT and E-to-Q SecA.
The Mg-MANT-ADP-binding affinity of WT (●) or mutant (■) variants of BsSecA (panel A) or EcSecA (panel B) were measured at temperatures from 5–30 °C in KEMT buffer (pH 7.6) using the fluorescence anisotropy assay shown in Fig. 2 with 900 nM Mg-MANT-ADP.