Figure 5.
A) Individual rat performance on the bradykinesia assessment task. Symbols indicate when an animal regained 50% of pre-lesion forelimb function. X indicates that an animal that did not regain 50% of forelimb function at any point during therapy. All rats that received VNS during rehab regained 50% of forelimb function by week 2 (squares). One animal in both the rehab alone (circles) and VNS after rehab group (triangles) did not regain 50% of forelimb function. B) Number of days for each group to regain 50% of forelimb function based on lever press success rate performance. The VNS during rehab group demonstrated 50% recovery of pre-lesion performance within the first week of therapy, while rats that received rehab alone reached 50% recovery during the third week of therapy on average. Data are means ± S.E.M. (* p <0.05).