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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Adv Healthc Mater. 2014 Mar 26;3(8):1283–1291. doi: 10.1002/adhm.201400026

Figure 2.

Figure 2

(a) Chemical structures of SV119 and SW120 that bind specifically to the sigma-2 receptor. (b) The relative geometric mean fluorescence intensities (GMFI) recorded from the CSCs and non-CSCs. (c) Flow cytometry analyses of the CSCs that were pre-treated with SV119 for 1 h and then incubated with SW120 (50 nM) for 0.5 h. Cells incubated with PBS were used as a control. (d) Flow cytometry analyses of the non-CSCs that were pre-treated and incubated using the same protocol as in (C). The CSCs (ALDHhi population) and non-CSCs (ALDHlow population) derived from the mammospheres were labeled using the ALDEFLUOR kit and separately collected using the BD FACSAria III cell sorter.