Table 1. Significantly altered circulating miRNAs in transgenic mice with mammary tumors.

No normalization was used in this analysis.

	MMTV-Her2/Neu vs. control		MMTV-PyMT vs. control
miRNA	P value	Fold change	P value	Fold change
MMTV-Her2/Neu specific
miR-486	0.0001	−6.54	0.72	−1.11
miR-7a	0.0025	58.47	0.69	−1.48
miR-743a	0.007	2.03	1	−1
miR-381	0.0079	2.66	1	−1
miR-139-3p	0.015	88.62	0.03	46.2
miR-129-3p	0.016	35.61	0.492	2.39
miR-191	0.018	−4.45	0.21	2.00
miR-34a	0.019	40.757	0.606	2.00
MMTV-PyMT specific
miR-136	0.978	1.01	2.19E-06	81.41
miR-202-3p	0.537	−1.15	0.00046	3.35
miR-574-3p	0.50	1.34	0.00094	7.92
miR-146b	0.271	2.15	0.001	21.47
miR-134	0.0248	6.4	0.0015	21.7
miR-667	0.668	1.18	0.0017	5.28
miR-685	0.633	1.43	0.002	21.7
miR-24	0.03	4.2	0.003	8.9
miR-132	0.019	49.99	0.0038	209.42
miR-542-5p	0.45	2.6	0.005	97.17
miR-324-3p	0.11	4.05	0.006	17.07
miR-223	0.919	−1.06	0.0066	8.17
miR-92a	0.718	−1.15	0.007	3.94
miR-342-3p	0.08	2.73	0.007	5.83
miR-410	0.857	1.31	0.0096	127.559
miR-200a	0.038	7.07	0.01	13.62
miR-484	0.639	−1.23	0.01	4.05
miR-139-5p	0.715	1.255	0.01	6.96
miR-429	0.035	53.58	0.01	173.95
miR-187	0.94	1.07	0.01	19.58
miR-30a	0.141	2.67	0.014	6.37
miR-511	0.031	15.93	0.015	25.74
miR-423-5p	0.51	−1.52	0.016	6.09
miR-335-5p	0.364	5.14	0.016	155.23
miR-146a	0.303	1.93	0.016	5.9
miR-125a-3p	0.238	13.7	0.019	359.00
Commonly deregulated in both transgenic mice
miR-193b	0.009	6.7	0.0001	36.2
miR151-3p	0.0072	5.199	0.0003	13.73
miR-27b	0.007	171.86	0.0004	3013.24
miR-671-3p	0.0095	47.41	0.0013	220.48
miR-200b	0.014	9.82	0.018	8.7
miR-183	0.016	23.44	0.004	56.17
miR-210	0.02	6.53	0.00082	27.37
miR-132	0.02	49.99	0.0038	209.4