. Author manuscript; available in PMC: 2015 Sep 1.

Published in final edited form as: Crit Care Med. 2014 Sep;42(9):2058–2068. doi: 10.1097/CCM.0000000000000418

Table 3.

Baseline severity of lung injury by urine NNAL level

	Smoking Status by Urine NNAL
	Nonsmoker 0 pg/ml (N=143)	Passive smoker >0, <47.3 pg/ml (N=101)	Active smoker >=47.3 pg/ml (N=137)	p-value
Lung Injury Score, mean ± SD	2.7 ± 0.6	2.8 ± 0.6	2.8 ± 0.5	0.40
PaO₂/FiO₂ (mm Hg), mean ± SD	121 ± 53	123 ± 60	130 ± 79	0.48
PEEP (cm H₂O), mean ± SD	8.8 ± 3.6	8.8 ± 3.6	9.3 ± 3.3	0.41
Compliance (mL/cm H₂O), mean ± SD	35 ± 16	33 ± 19	33 ± 14	0.45
CXR quadrants with opacities, median [IQR]	4 [3, 4]	4 [3, 4]	4 [3, 4]	0.44
Oxygenation Index, median [IQR]	10 [6, 16]	13 [7 , 21]	11 [8, 18]	0.20
Berlin Definition of ARDS, n (%)				0.37
Mild ARDS (n=42)	11 (8)	14 (14)	17 (13)
Moderate ARDS (n=178)	73 (53)	41 (41)	64 (48)
Severe ARDS (n=152)	55 (40)	44 (44)	53 (40)

Definition of abbreviations: FiO₂ = fraction of inspired oxygen; NNAL = 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol; PaO₂ = partial pressure of oxygen in arterial blood; PEEP = positive end-expiratory pressure; SD = standard deviation