Table 5.
Predictor | OR for death at 60-daysa | 95% CI | P-value |
---|---|---|---|
Smoking status by urine NNAL | |||
Nonsmoker | (reference) | ||
Passive smoker | 1.00 | 0.49 – 2.02 | 1.0 |
Active smoker | 0.58 | 0.28 – 1.22 | 0.15 |
Age, yr | 1.04 | 1.02 – 1.06 | <0.001 |
Alcohol useb | |||
Low-risk | (reference) | ||
Abstinence | 0.89 | 0.43 – 1.82 | 0.75 |
Mild to moderate alcohol misuse | 0.67 | 0.13 – 3.47 | 0.63 |
Severe alcohol misuse | 1.57 | 0.55 – 4.50 | 0.40 |
Unknown | 2.93 | 1.21 – 7.09 | 0.02 |
APACHE III | 1.02 | 1.01 – 1.03 | <0.001 |
Definition of abbreviations: APACHE III = Acute Physiology and Chronic Health Evaluation III; NNAL = 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.
Multivariate logistic regression with backward selection was performed; covariates with p<0.10 were retained in final model. Original model, which also contained comorbidities, primary risk factor of lung injury, and septic shock, is shown in Online Supplement Table S4.
As defined by Alcohol Use Disorders Identification Test (AUDIT) scores (Online Supplement, Table S1)