. Author manuscript; available in PMC: 2015 Sep 1.

Published in final edited form as: Crit Care Med. 2014 Sep;42(9):2058–2068. doi: 10.1097/CCM.0000000000000418

Table 5.

Multivariate analysis for 60-day mortality

Predictor	OR for death at 60-days^a	95% CI	P-value
Smoking status by urine NNAL
Nonsmoker	(reference)
Passive smoker	1.00	0.49 – 2.02	1.0
Active smoker	0.58	0.28 – 1.22	0.15
Age, yr	1.04	1.02 – 1.06	<0.001
Alcohol use^b
Low-risk	(reference)
Abstinence	0.89	0.43 – 1.82	0.75
Mild to moderate alcohol misuse	0.67	0.13 – 3.47	0.63
Severe alcohol misuse	1.57	0.55 – 4.50	0.40
Unknown	2.93	1.21 – 7.09	0.02
APACHE III	1.02	1.01 – 1.03	<0.001

Definition of abbreviations: APACHE III = Acute Physiology and Chronic Health Evaluation III; NNAL = 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.

Multivariate logistic regression with backward selection was performed; covariates with p<0.10 were retained in final model. Original model, which also contained comorbidities, primary risk factor of lung injury, and septic shock, is shown in Online Supplement Table S4.

As defined by Alcohol Use Disorders Identification Test (AUDIT) scores (Online Supplement, Table S1)