Skip to main content
. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Dev Biol. 2014 Jun 20;393(1):149–159. doi: 10.1016/j.ydbio.2014.06.011

Figure 6. gata1 is required to initiate mpx expression in the ICM region, but later represses it.

Figure 6

(A-H) pu.1 expression is greatly increased (n=16/16 and 31/31) while mpx expression is greatly reduced (n=66/66 and 26/26) as analyzed by ISH in gata1 MO knockdown embryos at the 20-somite (A-D) and 24-somite (E-H) stages, respectively. (I-P) Both pu.1 and mpx expression are greatly increased in gata1 morphant embryos at 26 hpf and 32 hpf (n=35/35 and 30/33 for pu.1 expression; n=27/31 and 21/24 for mpx expression at 26 hpf and 32 hpf, respectively). Dorsal is up and anterior is to the left in all panels.