Table 2.

Scope studies for hydroxamic acid synthesis.

entrya	product		yield (%)b
1		R7 = H	83
2		R7 = OMe	77
3		R7 = Me	85
4		R7 = CF3	81
5		R7 = CN	72
6		R7 = Br	76
7		R6 = F	79
8		R6 = OMe	0c
9		X = O	78
10d		X = NTs	53
11d			64
12d			58

^aReactions conducted using 2.5 mol% Ru(bpy)₃Cl₂, 2.1 equiv 5, and 0.1 equiv CSA unless otherwise noted.

^bValues represent the averaged isolated yields from two reproducible experiments.

^cQuinolinone 10 was isolated in 54% yield (Scheme 2).

^dReaction conducted using 3 equiv of 5 and 1 equiv of CSA.