Table 1.
Catalytic N-oxidation of quinolinea
| |||
|---|---|---|---|
| Entry | Catalyst (x mol%) | Solvent (temperature/°C) | Yield(%) |
| 1 | — | CH3CN (50) | 0 |
| 2 | — | C2H5OH (50) | 0 |
| 3 | CF3SO3H (10) | CH3CN (50) | 0 |
| 4 | CF3CO2H (10) | CH3CN (50) | 0 |
| 5 | Sc(O3SCF3)3 (10) | CH3CN (50) | 13 |
| 6 | FeCl3 (10) | CH3CN (50) | 0 |
| 7 | CuCl2 (10) | CH3CN (50) | 0 |
| 8 | [Ru(p-cumene)Cl]2 (10) | CH3CN (50) | 0 |
| 9 | Na2WO4 (10) | CH3CN (50) | 0 |
| 10 | Mo(O2)2O·HMPA (10) | CH3CN (50) | 22 |
| 11 | MoO3 (10) | CH3CN (50) | 19 |
| 12 | Na2MoO4 (10) | CH3CN (50) | 33 |
| 13 | MoO2Cl2 (10) | CH3CN (50) | 13 |
| 14 | Mo(CO)6 (10) | CH3CN (50) | 14 |
| 15 | (NH4)2Mo7O24 (10) | CH3CN (50) | 16 |
| 16 | H3PMo12O40 (10) | C2H5OH (50) | 39 |
| 17 | H3PMo12O40 (10) | CH3CN (70) | 95 |
| 18b | H3PMo12O40 (1) | CH3CN (50) | 97 |
| 19 | H3PMo12O40 (0.5) | CH3CN (50) | 99 |
a
Reaction conditions: csubstrate = 1 mol L−1, except if stated otherwise;
b
30% aqueous H2O2. csubstrate = 2 mol L−1.