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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: J Immunol. 2014 Jul 25;193(5):2519–2530. doi: 10.4049/jimmunol.1400276

Figure 7. HK C. albicans requires CR3 for IL-1β, CR3 as well as dectin-1 for cell death, while live C. albicans partially requires CR3 for IL-1β production.

Figure 7

Pam2CSK4 primed BMDC from C57BL/6, Clec7a−/−, Itgam−/− mice were stimulated with HK C. albicans or live C. albicans at 10:1 for 6h, ATP or nigericin for 1h. IL-1β released in the supernatants was measured by ELISA (A, B) and cell viability by cell-titer glo assay (C, D). Statistical analysis was performed on results in panels A and B as described in the Materials and Methods section.