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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: J Immunol. 2014 Jul 23;193(5):2538–2545. doi: 10.4049/jimmunol.1400675

Fig. 1. Differential effect of IKKβ inhibition on virus-induced type 1 IFN expression in cDCs and pDCs.

Fig. 1

(A) Effect of IKKβ inhibitor PS-1145 on SeV infection-induced type 1 IFN production by splenic pDCs and BM-derived pDCs determined by ELISA. (B) Effect of PS-1145 on SeV infection-induced IFN-β and IFN-α protein expression in cDCs determined by ELISA. All virus infections were for 6h. SeV: sendai virus. PS: PS-1145. Sp_pDCs: splenic plasmacytoid dendritic cells. BM_pDCs: bone marrow-derived plasmacytoid dendritic cells generated by FLT-3 ligand. P-values are specified as *<0.05, **<0.01, ***<0.001. Representative results from 3 independent experiments are shown.