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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: J Immunol. 2014 Jul 23;193(5):2538–2545. doi: 10.4049/jimmunol.1400675

Fig. 4. IKKβ is essential for TLR but not RLR induced type 1 IFN and inflammatory cytokine expression in MEFs.

Fig. 4

(A) IFN-β, IFN-α4, and IFN-α (non4) mRNA expression in IKKβ+/+ and IKKβ−/− MEFs induced by LPS, SeV or NDV infection as determined by real-time PCR. (B) TNFα mRNA expression in IKKβ+/+ and IKKβ−/− MEFs induced by LPS, SeV or NDV infection as determined by real-time PCR. (C) IL-6 mRNA expression in IKKβ+/+ and IKKβ−/− MEFs induced by LPS, SeV or NDV infection as determined by real-time PCR. P-values are specified as *<0.05, **<0.01, ***<0.001. Representative results from 3 independent MEF isolates are shown.