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. Author manuscript; available in PMC: 2014 Aug 17.
Published in final edited form as: Mol Cell Neurosci. 2014 Apr 28;0:1–12. doi: 10.1016/j.mcn.2014.04.006

Figure 2.

Figure 2

miR-124 is enriched at synapses while GluA2 mRNA is de-enriched.

(A) Synaptosome fractions were prepared from adult forebrain. Immunoblotting shows enrichment for PSD-95 in the synaptosome fraction (5 μg of total protein was loaded in each lane). (B) Comparative RT-qPCR on RNA extracted from total and synaptosome fractions of mouse forebrain. Relative ratios are plotted on the y-axis. Significance was determined by one-way ANOVA with Bonferroni correction. Pairwise comparisons between the ratios for Camk2α vs. GluA2 and GluA2 vs. miR-124 were significantly different (p<0.01 and p<0.001 respectively). GluA2 and miR-124 were not significantly different (p>0.05). Error bars show S.E.M. N = 3 independent experiments.