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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Biochim Biophys Acta. 2014 Jun 18;1839(9):773–784. doi: 10.1016/j.bbagrm.2014.06.007

Figure 4. Different combinations of lncRNA transgenes can increase or decrease female viability.

Figure 4

Female viability relative to males as percent, when females with different lncRNA combinations are crossed to males with reduced X chromosome counting genes (sis-a1, sis- bsc3-1). For all crosses, only one copy of the lncRNA transgene is present. Viability of w1118 females without a transgene was 24%. Arrow direction indicates the strand expressed; 5’ is to the left. Graphic of promoter and R1 and R2 regions at bottom shows location of region expressed in each line. Light gray is R2 and dark line represents R1 region. Transgenes of the combined regions (R1 + R2) shown with both tones. They encompass all of the R1 and R2 regions and the short ~35bp region between them. The effect on females with only the (R1+ R2) sense or antisense lncRNA is in lines (a) and (g), and is relatively mild. R1 lines represented: 40.3 and 28.1; R2 lines represented: A3 and S5.