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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Biochim Biophys Acta. 2014 Jun 18;1839(9):773–784. doi: 10.1016/j.bbagrm.2014.06.007

Figure 6. lncRNAs alter H3K4me3 and H3K27me3 levels.

Figure 6

lncRNA expression alters epigenetic marks associated with PcG/trxG proteins. ChIPs of H3K4me3 and H3K27me3 (A) reported as % input, scored immediately 3’ of SxlPe (+138 bp avg. position) in Ore R and X^X 7BO (females), as well as the projected male signal calculated by subtracting the female contribution from Ore R (obtained by multiplying Ore R signal by 3, giving the total from the avg. of 3 contributing X chromosomes, and subtracting 2 times the female signal which represents the avg. of 2 contributing X chromosomes). ChIP signal of H3K27me3 (B) and H3K4me3 (C) in OreR and lncRNA lines. NI is non-immune serum. Astersisks show significant changes relative to wild-type, *** P-value <0.0005. ChIP experiments were repeated at least twice. Highest P-value compared to non-immune <0.0001. Error bars represent mean +/− SEM.