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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Psychopharmacology (Berl). 2014 Apr 5;231(17):3325–3332. doi: 10.1007/s00213-014-3546-x

Table 2.

Eudismic ratios for enantiomer pairs in the seizure tests and the test of motor toxicity

Enantiomer Pairs Eudismic Ratioa
6-Hzb PTZb MESb Horizontal Screenc
5α,3α-A– ent-5α,3α-A 2.4 2.3 1.6 2.6
5β,3α-A– ent-5β,3α-A 4.9 5.3 2.0 4.1
a

Ratio of the ED50 or TD50 values from Table 1 of distomer (natural steroids) to that of eutomer (entsteroids).

b

Seizure tests.

c

Test of motor toxicity reflecting sedation or muscle relaxation.