Table 4.
Results of models 1-4 of maternal and paternal SMI predicting ASD and ADHD
Predictors | Model 1 | Model 2 | Model 3 | Model 4 | ||||
---|---|---|---|---|---|---|---|---|
HR | 95% CI | HR | 95% CI | HR | 95% CI | HR | 95% CI | |
ASD | ||||||||
Maternal SMI | 2.04* | 1.78-2.34 | 1.99* | 1.74-2.28 | 1.73* | 1.50-1.99 | 1.72* | 1.46-2.02 |
Paternal SMI | 1.98* | 1.72-2.28 | 1.92* | 1.66-2.21 | 1.59* | 1.37-1.85 | 1.56* | 1.31-1.86 |
ADHD | ||||||||
Maternal SMI | 2.16* | 1.97-2.37 | 2.09* | 1.90-2.29 | 1.59* | 1.44-1.75 | 1.56* | 1.39-1.74 |
Paternal SMI | 2.21* | 2.01-2.43 | 2.13* | 1.94-2.35 | 1.47* | 1.32-1.62 | 1.36* | 1.21-1.54 |
Note: SMI= severe mental illness, ASD = Autism Spectrum Disorder, ADHD = Attention Deficit Hyperactivity Disorder, HR = hazard ratio, CI = confidence interval,
p<0.05. Model 1 controlled for offspring sex and parity. Model 2 additionally controlled for SMI in the other parent. Model 3 additionally controlled for all measured covariates. Model 4 additionally controlled for gestational age, birth weight, and small for gestational age.