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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: J Immunol. 2014 Jul 25;193(5):2157–2167. doi: 10.4049/jimmunol.1302702

Figure 5. Effect of TD on adoptive EAE model.

Figure 5

A: EAE was induced in C57BL/6 mice by injection of MOG35-55 with or without TD. Encephalitogenic cells were collected from these mice as described under the Materials and Methods and injected into recipient mice (wild-type). The recipient mice were irradiated sublethally (500 rad) 16 hours before the injection. The clinical scores for EAE and body weight were determined as described under the Materials and Methods. B: EAE was induced in C57BL/6 mice by injection of MOG35-55. The encephalitogenic cells were prepared from EAE mice and injected into recipient mice with/without TD. The clinical scores for EAE and body weight were determined as described under the Materials and Methods. Data were presented as mean ± SD; *p<0.05, **p<0.01, ***p<0.001, compared with control group. n = 8 for each group. C: Lymph node cells were isolated from EAE mice with or without TD after 10 days of induction. The percentage of IFN-γ, IL-4 and IL-17 producing cells were measured by FACS. Data were presented as mean ± SD; *p<0.05, compared with EAE group. n = 4 for each group.