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. 2014 Jul 24;2014:637528. doi: 10.1155/2014/637528

Figure 5.

Figure 5

Ele reduced the effectiveness of apatinib on H22 solid tumor in mice. The H22 bearing mice were randomized into six groups (n = 9): 200 mg/kg apatinib group, 75 mg/kg Ele group, 50 mg/kg Ele + 200 mg/kg apatinib group, 75 mg/kg Ele + 200 mg/kg apatinib group, 100 mg/kg Ele + 200 mg/kg apatinib group, 75 mg/kg Ele + 100 mg/kg apatinib group, 75 mg/kg Ele + 300 mg/kg apatinib group, and H22-bearing mice as negative control group (NS group). All the mice were sacrificed after 8 days of treatment. Inhibition ratio (IR) was calculated using IR(%) = {(TVcontrol − TVtreat)/TVcontrol} × 100. *P < 0.05 versus apatinib, # P < 0.05 versus Ele.