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. 2014 Jul 24;2014:107501. doi: 10.1155/2014/107501

Table 1.

Protection of mitochondria and improvement of energy metabolism during MIRI.

Pharmacological action Methods Reference
Protect mitochondria and improve energy metabolism Reduce myocardial ATP delay ATP breakdown Nordlie et al. 2006 [5]
Protect Na+-K+-ATPase activity Wang et al. 2003 [6]
Stimulate synthesis of protein and RNA Zhu et al. 2010 [7]
Maintain the complete structure of biological membranes and myocardial fibers Shi et al. 1998 [8]
Reduce SDH and CCO deactivation Wang et al. 1998 [9]
Increase activity of Ca2+-ATPase and Ca2+-Mg2+-ATPase and regulate expression of the Bcl-2 gene Wan et al. 2001 [10]