Table 2.
Percent difference (95% confidence interval) in cord serum triglyceride by increasing quartile of selenium or copper, THREE study 2004–2005, n = 274
| Model | Q1 | Q2 | Q3 | Q4 | Test for trenda |
|---|---|---|---|---|---|
| Selenium (μg/l) | 42.0–62.0 | 63.0–69.0 | 70.0–78.0 | 79.0–114.0 | |
| Model 1b | 1.00 (referent) | 7.6 (−5.9, 23.1) | 11.0 (−2.9, 27.0) | 24.2 (8.1, 42.6) | 0.008 |
| Model 2c | 1.00 (referent) | 11.8 (−1.1, 26.5) | 13.1 (−0.1, 28.2) | 22.3 (7.1, 39.7) | 0.005 |
| Model 3cd | 1.00 (referent) | 6.1 (−5.9, 19.6) | 5.5 (−6.7, 19.2) | 6.3 (−7.5, 22.2) | 0.457 |
| Copper (μg/dl) | 12.1–28.4 | 28.5–38.0 | 38.1–51.6 | 51.7–109.0 | |
| Model 1b | 1.00 (referent) | 12.4 (−1.2, 28.0) | 28.6 (12.7, 46.8) | 50.6 (31.6, 72.2) | < 0.001 |
| Model 2c | 1.00 (referent) | 15.9 (2.6, 30.8) | 30.3 (14.8, 48.0) | 43.8 (25.9, 64.3) | < 0.001 |
| Model 3dd | 1.00 (referent) | 15.0 (1.8, 30.0) | 27.8 (11.7, 46.2) | 40.7 (22.1, 62.1) | < 0.001 |
THREE, Tracking Health Related to Environmental Exposures; Q1, first quartile; Q2, second quartile; Q3, third quartile; Q4, fourth quartile; HUFA, highly unsaturated fatty acid.
a
Based on regression model using selenium or ln(copper) instead of quartiles.
b
Adjusted for gestational age (quadratic).
c
Adjusted for gestational age (quadratic), maternal age, maternal race, maternal smoking, primiparity, low birth weight, prepregnancy body mass index (quadratic), n-3 HUFAs/total HUFAs, and ln(methyl mercury).
d
Adjusted for variables in Model 2 as well as (3c) ln(copper) or (3d) selenium.