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. 2014 Aug 18;4:5845. doi: 10.1038/srep05845

Table 1. Inhibitory activity of NAb and NNIAb when primary pDC/MoDC were used as HIV-1BaL target cells. IC90: concentration (µg/ml) of Ab necessary to reduced by 90% the number of infected cells; -, no inhibitory activity detected at 100 µg/ml of Ab. NNNIAb, non-neutralizing non-inhibitory anti-HIV-1 Ab. Values are the mean of 3–7 different independent experiments performed on cells purified from different independent healthy blood donors.

  IC90 (µg/ml)
  NAb    
  2F5 4E10 10E8 b12 2G12 447-52D VRC01 PGT121 10-1074
pDC 80 100 100 8 10 80 7 1.3 6
MoDC 1 5 20 1 1 2 1 0.2 0.6
  NNIAb NNNIAb    
  246-D 4B3 3D6            
pDC - - -            
MoDC 45 45 -