Table 1.
0 h | 2 h | 4 h | 6 h | |
---|---|---|---|---|
HR (beats/min) |
|
|
|
|
Group 1 |
152 ± 5 |
155 ± 7 |
154 ± 8 |
157 ± 8 |
Group 2 |
155 ± 7 |
158 ± 6 |
156 ± 9 |
160 ± 7 |
Group 3 |
155 ± 5 |
162 ± 5*# |
168 ± 9*#Δ |
175 ± 8* |
Group 4 |
154 ± 6 |
160 ± 6 |
168 ± 8*Δ |
167 ± 7* |
pH |
|
|
|
|
Group 1 |
7.32 ± 0.06 |
7.33 ± 0.03 |
7.29 ± 0.10 |
7.31 ± 0.01 |
Group 2 |
7.25 ± 0.04 |
7.26 ± 0.04 |
7.24 ± 0.03 |
7.21 ± 0.01 |
Group 3 |
7.25 ± 0.11# |
7.11 ± 0.18 |
7.23 ± 0.05 |
7.15 ± 0.14# |
Group 4 |
7.27 ± 0.05 |
7.18 ± 0.19 |
7.13 ± 0.11# |
7.15 ± 0.20 |
PaCO2 (mmHg) |
|
|
|
|
Group 1 |
36.88 ± 6.06 |
41.52 ± 12.41 |
40.18 ± 13.86 |
40.84 ± 10.62 |
Group 2 |
38.88 ± 6.66 |
42.52 ± 12.41 |
42.18 ± 10.86 |
44.84 ± 7.62 |
Group 3 |
41.43 ± 9.51 |
56.77 ± 22.75 |
49.15 ± 14.03 |
47.48 ± 14.15 |
Group 4 |
38.88 ± 6.66 |
48.52 ± 22.41 |
45.18 ± 13.86 |
47.84 ± 17.62 |
PaO2/FiO2(mmHg) |
|
|
|
|
Group 1 |
484.42 ± 28.34 |
475.50 ± 20.80 |
543.45 ± 61.56 |
423.20 ± 23.20 |
Group 2 |
430.95 ± 28.37 |
428.75 ± 37.50 |
431.25 ± 39.24◆ |
435.00 ± 31.62◆ |
Group 3 |
410.40 ± 28.36 |
335.55 ± 29.29*#Δ |
287.90 ± 54.84*#Δ |
292.83 ± 60.34*#Δ |
Group 4 |
441.43 ± 24.26 |
371.87 ± 20.35*# |
368.83 ± 55.29*#Δ◆ |
380.63 ± 56.83◆ |
MPAP (mmHg) |
|
|
|
|
Group 1 |
14 ± 1 |
14 ± 1 |
13 ± 3 |
12 ± 1 |
Group 2 |
16 ± 2 |
15 ± 2 |
14 ± 1 |
15 ± 2 |
Group 3 |
17 ± 3 |
24 ± 4*#Δ |
22 ± 4#Δ |
18 ± 4#§ |
Group 4 |
17 ± 4 |
19 ± 3#Δ◆ |
20 ± 2#Δ |
15 ± 2#§ |
CO(l/min) |
|
|
|
|
Group 1 |
2.95 ± 0.32 |
2.84 ± 0.24 |
2.84 ± 0.69 |
2.86 ± 0.53 |
Group 2 |
2.60 ± 1.00 |
2.62 ± 1.04 |
2.62 ± 1.08 |
2.73 ± 1.03 |
Group 3 |
2.88 ± 1.04 |
2.60 ± 1.14 |
2.71 ± 1.28 |
2.63 ± 1.19 |
Group 4 |
3.01 ± 0.64 |
2.62 ± 0.26 |
3.17 ± 0.54 |
3.20 ± 0.55 |
PVR(dyne.s.cm-5) |
|
|
|
|
Group 1 |
164.24 ± 45.61 |
200.94 ± 59.54 |
140.46 ± 55.84 |
171.59 ± 38.72 |
Group 2 |
301.25 ± 96.77# |
253.68 ± 99.09 |
299.52 ± 92.64# |
271.66 ± 93.89# |
Group 3 |
373.20 ± 89.09# |
601.01 ± 92.33*#Δ |
435.88 ± 99.63# |
327.09 ± 96.66#§ |
Group 4 | 335.88 ± 63.46# | 474.67 ± 87.91*# | 335.93 ± 43.84# | 239.86 ± 53.26*◆§ |
Note: Group 1: Sham group, Group 2: Ischemia group, Group 3: Reperfusion group, Group 4: Inhaled NO group. * and § P < 0.05 for the comparison with the parameters recorded at the time point before reperfusion and 2 hours after reperfusion within the same group, respectively. At the same time point among different groups,#P < 0.05 for the comparison with the Sham group,Δ P < 0.05 for the comparison with the Ischemia group,◆ P < 0.05 for the comparison with the Reperfusion group.