Table 3.

Risk of autism and ADHD in offspring when their parents were diagnosed with alcohol use disorder (AUD) before the birth of the offspring

DOI: http://dx.doi.org/10.7554/eLife.02917.005

AUD in parent	No. of offspring at risk	Person-years of follow-up	Autism				ADHD
			O	SIR	95% CI		O	SIR	95% CI
Risk in sons
Father	41832	410327	442	1.44	1.31	1.59	1555	2.60	2.48	2.74
Mother	8776	80,689	99	1.67	1.35	2.03	347	3.14	2.82	3.49
Parents	48704	472596	514	1.46	1.34	1.59	1778	2.61	2.49	2.73
Risk in daughters
Father	39684	390429	145	1.40	1.18	1.64	565	3.05	2.80	3.31
Mother	8457	77259	36	1.79	1.25	2.48	119	3.44	2.85	4.12
Parents	46299	450022	175	1.47	1.26	1.70	634	3.00	2.77	3.24
Risk in offspring
Father	81516	800756	587	1.43	1.32	1.55	2120	2.71	2.59	2.83
Mother	17233	157948	135	1.70	1.42	2.01	466	3.22	2.93	3.52
Parents	95003	922618	689	1.46	1.36	1.58	2412	2.70	2.59	2.81

O, observed number of cases; SIR, standardized incidence ratio; CI, confidence interval.

Bold type, 95% CI does not include 1.00.