Table 4.
Risk of autism and ADHD in adoptees when their biological or adoptive parents were diagnosed with alcohol use disorder (AUD)
No. of offspring at risk | Person-years of follow-up | Autism | ADHD | |||||||
---|---|---|---|---|---|---|---|---|---|---|
O | SIR | 95% CI | O | SIR | 95% CI | |||||
Biological parents with AUD | ||||||||||
Father | 2175 | 51746 | 16 | 2.15 | 1.23 | 3.50 | 53 | 2.63 | 1.97 | 3.44 |
Mother | 1381 | 32745 | 10 | 1.81 | 0.86 | 3.35 | 18 | 1.21 | 0.72 | 1.92 |
Parents | 3251 | 77310 | 19 | 1.75 | 1.05 | 2.74 | 58 | 1.91 | 1.45 | 2.47 |
Adoptive parents with AUD | ||||||||||
Father | 457 | 10,839 | 1 | 0.75 | 0.00 | 4.28 | 7 | 1.78 | 0.70 | 3.68 |
Mother | 229 | 5443 | 0 | 4 | 1.93 | 0.50 | 4.98 | |||
Parents | 654 | 15546 | 1 | 0.51 | 0.00 | 2.93 | 9 | 1.59 | 0.72 | 3.04 |
O, observed number of cases; SIR, standardized incidence ratio; CI, confidence interval.
Bold type, 95% CI does not include 1.00.