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. 2014 Aug 19;3:e02917. doi: 10.7554/eLife.02917

Table 4.

Risk of autism and ADHD in adoptees when their biological or adoptive parents were diagnosed with alcohol use disorder (AUD)

DOI: http://dx.doi.org/10.7554/eLife.02917.006

No. of offspring at risk Person-years of follow-up Autism ADHD
O SIR 95% CI O SIR 95% CI
Biological parents with AUD
 Father 2175 51746 16 2.15 1.23 3.50 53 2.63 1.97 3.44
 Mother 1381 32745 10 1.81 0.86 3.35 18 1.21 0.72 1.92
 Parents 3251 77310 19 1.75 1.05 2.74 58 1.91 1.45 2.47
Adoptive parents with AUD
 Father 457 10,839 1 0.75 0.00 4.28 7 1.78 0.70 3.68
 Mother 229 5443 0 4 1.93 0.50 4.98
 Parents 654 15546 1 0.51 0.00 2.93 9 1.59 0.72 3.04

O, observed number of cases; SIR, standardized incidence ratio; CI, confidence interval.

Bold type, 95% CI does not include 1.00.