Table 1.

The therapeutic stakes of prostate cancer.

	Life-threatening	Consequences of conventional curative treatments (radical prostatectomy or radiation therapy)	Alternative therapeutic options
Indolent prostate cancer	No	Over-treatment (unjustified deterioration of quality of life)	Active surveillance
Intermediate prostate cancer	Yes	Definitive cure (justified deterioration of quality of life)	A currently unknown one without deterioration of quality of life
High-grade prostate cancer	Yes	Ineffective treatment (incomplete tumor destruction/removal and local or metastatic recurrence)	Androgen deprivation as a unique option or within a (neo-) adjuvant association