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. Author manuscript; available in PMC: 2014 Aug 18.
Published in final edited form as: Transplantation. 2009 Mar 27;87(6):805–812. doi: 10.1097/TP.0b013e318199c34f

Figure 1.

Figure 1

Histopathologic features of failed heart grafts. Graft failure occurred after 24 hours in Exp 2, showing (A) hemorrhage, thrombosis and infarction (H&E, x400), (B) fibrin deposition (MSB, x400), and (C) platelet accumulation (IHC, x400). IgM (D), IgG (E), and complement C3 (F) deposition (all indicated by brown staining - arrows) were present in the heart of Exp 3 that underwent failure at 7 days from AHXR (x400). Graft failure occurred on day 6 in Exp 6, showing significant neutrophil (H&E, x200) (G) and macrophage (H) infiltration, with relatively less T (I) and B (J) cell infiltration (all IHC, x200, stained brown).