TABLE 2.
Radiation Dose Estimates for [18F]SPA-RQ in Standard Reference Man
| Target organ | Thin-slice µGy/MBq |
Bisected |
2D planar |
||
|---|---|---|---|---|---|
| µGy/MBq | Ratio to thin-slice | µGy/MBq | Ratio to thin-slice | ||
| Lungs | 81.8 | 81.2 | 0.99 | 80.1 | 0.98 |
| ULI wall | 78.2 | 67.6 | 0.86 | 58.2 | 0.74 |
| Small intestine | 69.5 | 60.2 | 0.87 | 52 | 0.75 |
| Urinary bladder wall | 56.8 | 57.4 | 1.01 | 58.4 | 1.03 |
| Kidneys | 56.4 | 68.3 | 1.21 | 92 | 1.63 |
| Thyroid | 31.3 | 41.7 | 1.33 | 61.6 | 1.97 |
| Liver | 30.2 | 27.6 | 0.91 | 30.4 | 1.01 |
| LLI wall | 28.9 | 25.7 | 0.89 | 22.6 | 0.78 |
| Red marrow | 28.1 | 15.8 | 0.56 | 14.8 | 0.53 |
| Osteogenic cells | 18.2 | 12.6 | 0.69 | 12 | 0.66 |
| Testes | 17.4 | 30.5 | 1.76 | 45.2 | 2.6 |
| Ovaries | 16.9 | 15.7 | 0.93 | 13.4 | 0.79 |
| Brain | 15.8 | 16.5 | 1.04 | 16.8 | 1.06 |
| Gallbladder wall | 15.7 | 15.2 | 0.97 | 15.2 | 0.97 |
| Heart wall | 15.5 | 19.7 | 1.28 | 35.9 | 2.32 |
| Uterus | 15.3 | 14.8 | 0.97 | 13.8 | 0.9 |
| Adrenals | 12.3 | 12.3 | 1.00 | 13.1 | 1.06 |
| Pancreas | 10.9 | 11.3 | 1.04 | 11.8 | 1.08 |
| Total body | 10.4 | 10.3 | 0.99 | 10.3 | 0.99 |
| Stomach wall | 9.2 | 9.7 | 1.05 | 9.6 | 1.05 |
| Spleen | 8.5 | 9.4 | 1.1 | 9.9 | 1.16 |
| Thymus | 7.5 | 8.2 | 1.1 | 8.6 | 1.15 |
| Muscle | 6.8 | 7.3 | 1.07 | 7.2 | 1.05 |
| Breasts | 6.3 | 6.8 | 1.09 | 6.9 | 1.11 |
| Skin | 4.1 | 4.6 | 1.14 | 4.6 | 1.12 |
| µSv/MBq | µSv/MBq | Ratio to thin-slice | µSv/MBq | Ratio to thin-slice | |
| ED equivalent | 37.6 | 37.3 | 0.99 | 40.6 | 1.08 |
| ED | 29.5 | 29.3 | 0.99 | 32.3 | 1.10 |
A 2.4-h urine voiding interval was assumed for all 3 methods.