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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Anat Rec (Hoboken). 2014 Sep;297(9):1637–1649. doi: 10.1002/ar.22980

Figure 3.

Figure 3

Localization and movement of chaperones in response to stress in vertebrate sarcomeric structures. Myosin chaperones Hsp90 and UNC-45 are held in reserve in the Z-disk until cellular stress induces rapid localization to the A-band. Similarly, the intermediate filament chaperones αB-crystallin and Hsp25/27 are located in the cytosol and localize to titin near the Z-disk upon stress to the sarcomere.