Table 3.
Comparison of solution and solvent-free G-quadruplex structures.a
| Systemb,c | Solution | Solvent-free |
|---|---|---|
| NMR/CD | IMS/modeling | |
| 4 × T1 | Parallel | Parallel |
| 2 × T1 | Mixed | Antiparallel |
| T3.5 | Antiparallel | Antiparallel |
| T4 | Antiparallel | Antiparallel |
| T6 | Antiparallel | Antiparallel |
| Pu22 | Parallel | Parallel |
| Pu27 | Parallel | Parallel |
a
Data from Refs. [104] and [105].
b
T1 = ATTGGG. T3.5 = GGG(ATTGGG)3. Pu22 = GAGGGTGGGGAGGGTGGGGAAG. Pu27 = TGGG[Pu22]G.
c
Pu22 and Pu27 are from the c-myc oncogene promoter region.