Skip to main content
. 2014 Feb 5;22(9):1105–1110. doi: 10.1038/ejhg.2014.7

Figure 5.

Figure 5

Regulation of MYC expression by DLX5 in HEK293 and HeLa cells. (a) Luciferase assay for DLX5 Q186H. SNM and XNM: luciferase reporter plasmids driven by a MYC promoter (pGL2-XNM and pGL2-SNM). WT: expression plasmid of wild-type cDNA of human DLX5 (pcDNA3.1-WT DLX5). Mut: expression plasmid of mutant cDNA of human DLX5 186H (pcDNA3.1-Mut DLX5). Luciferase activity is relative to that of Renilla luciferase. (b) Luciferase assay for Q186H and Q178P in HeLa cells. WT+MT (186H): cotransfection with wide-type DLX5(WT) and 186H mutant plasmid. WT+MT (178P): cotransfection with wide-type DLX5(WT) and 178P mutant plasmid. Data are mean±SD. ***P<0.001.