Figure 2.
In situ hybridization patterns of myotilin expression in sections of different stages of chicken embryonic hearts. In all panels scale bar = 100 μm. Myo, myocardium; Endo, endocardium; AS, antisense RNA probe.
A. In an HH stage 15 embryo the myocardium (Myo) expresses a relatively high level of myotilin as compared with the endocardium (Endo). AS = anti-sense.
B. Section of an embryonic day 7 (HH stage 31) sense control.
C. Section of day 7 embryo hybridized with antisense probes (AS). As compared to the control section in panel B, only a low level of signal is detectable in the myocardium.
D. A slightly higher level of myotilin expression is apparent in the compact layer and trabeculae of the embryonic day 12 (HH 38) heart.
