Table 1. Mast cells (MCs) and mucosal mast cells (MMCs) exhibit similar maturation profiles despite differential cell culture conditions*.
| % Cells expressing surface marker/mean fluorescence intensity† | ||||||
|---|---|---|---|---|---|---|
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| Week 2 | Week 5 | |||||
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| Cell type | c-Kit | FcεRI | MHCI | c-Kit | FcεRI | MHCI |
| MCs | 44/49 | 38/244 | 53/82 | 80/180 | 88/26 | 98/78 |
| MMCs | 45/59 | 32/360 | 78/84 | 96/170 | 92/28 | 99/87 |
FcεRI, fragment crystal epsilon receptor I; MHCI, major histocompatibility complex I
*
Data from weeks 2 and 5 are shown to demonstrate ultimate maturation profiles. Results are representative of two independent experiments
†
Mean fluorescence intensity represents the average output of each fluorophore for the total events acquired