FIG 5.

MSCs expressing FGF10 accumulate in lung tumors. (A and B) Specimen from a 59-year-old woman with squamous lung cancer. (C and D) Specimen from an 81-year-old man with lung adenocarcinoma. (E and F) Specimen from a 59-year-old woman with squamous lung cancer. Lung specimens from lung cancer patients were stained with FITC- and PE-conjugated antibodies specific for CD90 (an essential marker for MSCs) and FGF10, respectively. Nuclei were counterstained with DAPI. Scale bars, 100 μm. The lung cancer regions and the normal lung regions are shown in panels A, C, and E and panels B, D, and F, respectively. In all panels, controls included the isotype-matched control antibodies (Ctrl Ab).