TABLE 2.

Downregulated genes in tongues from E13.5 Wnt1-Cre;Alk5^fl/fl and control mice

Gene function and name	Gene symbol	Fold changea	P valueb
Muscle differentiation
Tcap	Titin-cap	−1.61	0.003541
Myl3	Myosin, light polypeptide 3	−1.56	0.006601
Cav3	Caveolin3	−2.00	0.014199
Tnnc1	Troponin C, cardiac/slow skeletal	−1.64	0.021082
Tnnc2	Troponin C2, fast	−1.97	0.000987
Tnni1	Troponin I, skeletal, slow 1
Tnni2	Troponin I, skeletal, fast 2	−1.94	0.000210
Tnnt2	Troponin T2, cardiac	−1.82	0.000902
Tnnt3	Troponin T3, skeletal, fast	−2.35	0.000898
Casq1	Calsequestrin 1	−1.63	0.031895
Chrna1	Cholinergic receptor, nicotinic, alpha polypeptide 1	−1.72	0.002628
Acta1	Actin, alpha 1	−2.04	0.009624
Tmod1	Tropomodulin 1	−1.57	0.010005
Myf6	Myogenic factor 6	−2.41	0.044509
Fgf4	Fibroblast growth factor 4	−1.85	0.003976
Fgf6	Fibroblast growth factor 6	−2.26	0.000587
Connective tissue and tendon formation
Scx	Scleraxis	−2.40	4.01E−05
Thbs4	Thrombospondin 4	−3.24	2.23E−05
Col8a1	Collagen	−2.78	5.85E−06
Col19a1	Collagen	−2.48	0.002539
Col6a1	Collagen	−1.89	0.011672
Cstl5	Follistatin-like 5	−1.86	0.000436
Cbln5	Fibulin 5	−1.90	0.003835
Tgfb3	Transforming growth factor β3	−1.58	0.005932

^aFold change > 1.5.

^bP value < 0.05.