TABLE 2.

Specificity and serotype distribution of selected S. pneumoniae ribitol-5-phosphate transferases or glycosyltransferases inferred from known CPS structures

Homology group	Gene	Structure			S. pneumoniae serotype(s) possessing gene
		Donor	Linkage	Acceptor	CPS structure known	CPS structure unknown
81	wciO	Ribitol	5-P-2	β-Galf	6A, 6B, 33B, 33D
46	wcrO	Ribitol	5-P-3	β-Galf	33C, 34	35F, 36
87	wcrB	Ribitol	5-P-5	β-Galf	10F, 10A, 10B, 10C
149	whaI	Ribitol	5-P-6	β-Galf	39, 47F, 47A	43
24	wefM	Galp	α1-1	Ribitol-5-P	39
24	wcrC	Galp	α1-2	Ribitol-5-P	10A, 10C, 34, 47F, 47A	35F, 43
24	wcrF	Galp	α1-4	Ribitol-5-P	10B, 10F, 33B, 33D
25	wciF	GalNAc	β1-3	α-Gal	10F, 10A, 10B, 10C, 33B, 33C, 33D, 39	13, 36
32	wcrD	Galf	β1-3	β-GalNAc	10F,a 10A, 10B, 10C,a 33C, 34, 39, 47F	13, 35F
102	wcrG	Galp	β1-6	β-GalNAc	10A, 10B,a 39

^aThe gene of interest occurs as a pseudogene in this serotype (9).