TABLE 4.
Previously undescribed carbon source utilization predicted for iFpraus_v1.0 (F. prausnitzii A2-165) and experimental validation
| Carbon source | Relative in silico growth rate (h−1) | In vivo growth |
|---|---|---|
| Arbutin | No growth | No growth |
| Citrate | No growth | No growth |
| Fumarate | No growth | No growth |
| Inosine | 0.66 | Weak acid production |
| Lactose | 0.78 | Growth |
| Malate | 0.07 | No growth |
| Mannose | No growth | No growth |
| N-Acetylneuraminic acid | 0.98 | Growth |
| Salicin | No growth | No growth |
| Succinate | No growth | No growth |
a
Relative in silico growth was calculated with the predicted growth rate on glucose as a reference. A pH decrease of >0.2 was considered indicative of growth in vitro.