Table 1. Pre-randomization, clinical characteristics of patients with and without 1-year stress MPS and by treatment to REV versus MED.
| Characteristic | 1-Year MPS (n = 1,505) |
No MPS (n = 863) |
P value | REV (n = 738) |
MED (n = 767) |
P value |
|---|---|---|---|---|---|---|
| Age, Mean, SD | 62.3, 8.7 | 62.5, 9.3 | .57 | 62.1, 8.7 | 62.5, 8.7 | .33 |
| Male | 72.5% | 66.7% | .003 | 72.2% | 72.8% | .79 |
| Race/ethnicity subsets | ||||||
| White, non-Hispanic | 69.2% | 60.2% | <.001 | 68.1% | 70.2% | .89 |
| Black, non-Hispanic | 13.2% | 23.1% | 13.8% | 12.6% | ||
| Hispanic | 12.6% | 12.5% | 13.0% | 12.2% | ||
| Asian | 4.6% | 3.5% | 4.5% | 4.6% | ||
| Other | 0.5% | 0.8% | 0.5% | 0.4% | ||
| HbA1c (%), mean, SD | 7.6, 1.6 | 7.7, 1.6 | .20 | 7.6, 1.6 | 7.6, 1.6 | .44 |
| Duration of diabetes, mean, SD | 10.2, 8.3 | 10.9, 9.3 | .07 | 9.9, 8.1 | 10.5, 8.4 | .20 |
| Insulin treatment | 26.3% | 30.6% | .02 | 26.5% | 26.2% | .90 |
| History of MI | 30.9% | 34.0% | .12 | 29.5% | 32.3% | .26 |
| History of heart failure | 5.1% | 9.4% | <.001 | 5.3% | 4.9% | .71 |
| CCS Class ≤6 weeks | ||||||
| No angina | 40.5% | 37.4% | .003 | 38.0% | 42.9% | .004 |
| Class 1-2 | 42.4% | 42.7% | 41.4% | 43.3% | ||
| Class 3-4 + unstable | 17.1% | 19.9% | 20.6% | 13.8% | ||
| Prior PCI | 18.9% | 20.9% | .22 | 19.5% | 18.2% | .50 |
| Prior CABG | 5.3% | 8.3% | .004 | 4.1% | 6.5% | .03 |
| Angiographic CAD | ||||||
| No stenosis ≥50% | 6.1% | 8.0% | .24 | 6.8% | 5.5% | .78 |
| 1 Vessel with ≥50% stenosis | 31.1% | 30.4% | 30.8% | 31.5% | ||
| 2 Vessels with ≥50% stenosis | 36.7% | 34.1% | 36.6% | 36.8% | ||
| 3 Vessels with ≥50% stenosis | 26.0% | 27.5% | 25.8% | 26.2% | ||
| Proximal left arterial descending | 13.0% | 13.6% | .71 | 12.8% | 13.2% | .79 |
| ≥50% stenosis | ||||||
| Angiographic EF<50% | 14.1% | 23.3% | <.001 | 13.9% | 14.1% | .92 |
SD, Standard deviation; MI, myocardial infarction; CCS, Canadian Cardiovascular Society; PCI, percutaneous coronary intervention; CABG, coronary-artery bypass graft.