Table 6. Cox proportional-hazards models estimating time to cardiac death or MI among patients undergoing MPS (n = 1,505).
Predictor | Unadjusted | Adjusted for baseline risk factors* | Adjusted for baseline risk factors plus post-nuclear revascularization | |||
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HR | P value | HR | P value | HR | P value | |
Post-stress LVEF (per 5% decrease) | 1.08 | .082 | 0.98 | .711 | 0.98 | .748 |
% Abnormal myocardium (per 5% increase) | 1.12 | <.001 | 1.11 | .004 | 1.12 | .003 |
% Ischemic myocardium (per 5% increase) | 1.08 | .129 | 1.04 | .468 | 1.06 | .311 |
% Scarred myocardium (per 5% increase) | 1.16 | <.001 | 1.16 | .002 | 1.16 | .002 |
Unadjusted model estimates the independent effects of each variable.
Model 1 simultaneously adjusts for baseline patient characteristics, trial characteristics, and LVEF.
Model 2 estimates independent effects of each nuclear predictor when simultaneously adjusting for baseline patient characteristics, trial characteristics, LVEF.
Age, gender, history of MI, history of CHF, number of diseased vessels, post-stress LVEF, intended REV randomization stratum, assigned glycemic treatment, assigned cardiac treatment.